bulbine natalensis human studies

Again, this isn’t something that’s been confirmed in a human-based study but it’s something to keep in mind, especially if you have liver or kidney issues. It’s essential to note that except for one all studies analyzing the impacts of Bulbine Natalensis have been performed on rats instead of people. This can be converted into an estimated 8 mg/kg for a 60 kg human according to the Body Surface Area Conversions standards laid down by the Food and Drug Administration (FDA) [ 15 ]. This is an important finding for ProLensis™ as it provides the first peer-reviewed documentation of safety in humans. The cornerstone ingredient of Aggressive Strength is the one and only Bulbine Natalensis. There are few herbs that actually boost testosterone, fewer that really lower estrogen, but none that do both exceptionally well – except Bulbine Natalensis.. In one study, 25 mg to 50 mg per kilogram of bodyweight of Bulbine Natalensis was shown to increase testosterone levels as well as serum follicle stimulating and luteinizing hormone concentrations. Aqueous extract of Bulbine natalensis Baker (Asphodelaceae) stem at 25, 50 and 100 mg/kg body weight was investigated for anabolic and androgenic effects in male Wistar rats. The incisional wounds were used to test tensile strength of the healed wounds using a tensiometer.In the in vitro studies, neither extract caused cytotoxicity to either the fibroblast or keratinocyte cells. The dosing seems, in rats, to have a inverse U relationship to testosterone, a sem linear downwards relationship to estrogen. Bulbine Natalensis is a South African shrub that has been used in traditional medicine to treat a variety of conditions including diabetes and convulsions. The rodent data suggests a testosterone boost of 347% compared to baseline, while lowering estrogen by 35%. The optimal dosage for testosterone effects was found to be 50 mg/kg in rat studies. It has also been shown to exhibit potent aphrodisiac qualities. For decades in the strength, bodybuilding and sporting world athletes have searched for optimal testosterone production in order to improve performance, add muscle mass, improve recovery or, even aid sexual performance. you will end up with a total of 347% of your original level). July 14, 2012. It has great influence on cognition and sexuality, and currently it is used as a testosterone booster. Bulbine Natalensis is a type of herb from South Eastern and Southern African countries and has been used for years as a form of aphrodisiac and other health benefits. ©Copyright 1997-2015, Vocus PRW Holdings, LLC. Studies have shown that it increases circulating testosterone significantly with dosage of 50 mg/kg bodyweight. Despite the absence of human-based studies and trials (for now), I think Bulbine Natalensis could be of use to guys who want to increase their levels of testosterone and libido. Sports Nutrition Research has also announced that there are plans for The Center for Applied Health Science to conduct more human trials involving ProLensis™ in the future. In addition, a clinical study involving one human male showed this substance increased both his testosterone levels by 35%. The results are indicative of prosexual stimulatory potentials of Bulbine natalensis in male rats. While I agree with the overall assessment in this article, as I always say, what works in rats usually does not end up working in humans. He has over 12 years of experience in the fitness industry and he has been the driving creative force behind numerous e-books and training guides on muscle building, weight loss, and performance enhancement. These doses are currently only estimates, but … Looking through user reviews, you’ll find that the only common negative complaint is that certain brands didn’t work; there are no reports of any horror-story side effects. Increases Libido and Sexual Performance: In the same study from above, researchers found that rats given the 25 mg to 50 mg per kilogram of bodyweight dosage engaged in more frequent sexual behavior. Bulbine Natalensis Recommended Dosage, Benefits, & Side Effects In the fitness community, users typically consume Bulbine Natalensis with the goal of increasing testosterone and sex drive. Bulbine natalensis is a plant indigenous to Africa, traditionally used as an aphrodisiac and tonic in tribesmen. The results of the study are to be published in the highly esteemed scientific Journal of the International Society of Sports Nutrition (JISSN). Although no human research can be found for the herb’s benefits, animal studies are promising: Bulbine (25 and 50 mg/kg body weight) enhances sexual behavior with effects similar to Viagrain rats This study fed 75 healthy male rats different amounts of bulbine natalensis along with a group of placebo and com… Editor’s Note: While the potential increase in DHT does not concern me, as noted several times throughout other articles on iTestosterone; I prefer to focus heavily on supplements proven in human based case studies. Unlike hyped supplements such as tribulus (that don't increase testosterone) the South African herb Bulbine Natalensis works and has been shown in studies to increase testosterone by a whopping 347% and crush estrogen by 35%. This testosterone booster has only recently come to light in Western fitness circles, but demonstrates very positive results so far.. David is an avid traveler and loves to hike. In 2009 researchers at the University of Ford Hare in South Africa published the results of an animal study in which they had given male rats water-based extracts of Bulbine natalensis for a week. The findings were presented at the recent International Society of Sports Nutrition (ISSN) conference held in Clearwater beach, Florida in June 2012. ... given the significance of the results in all of the studies undertaken so far, there is a strong probability that the effects can be seen in human equivalent doses. The photo shows Bulbine natalensis.Its Zulu name is ibhucu; Afrikaners call it rooiwortel.Herbalists sometimes prescribe the root of the plant for men with impotence problems. Vocus, PRWeb, and Publicity Wire are trademarks or registered trademarks of Vocus, Inc. or Vocus PRW Holdings, LLC. David Sautter is a NASM-certified personal trainer, NASM-certified fitness nutrition specialist, ACE-certified sports conditioning specialist, and health and fitness writer featured in Cellucor and Workout Labs. The photo shows the African botanical Bulbine natalensis. In my personal opinion, there is no reason to believe a nutrient will provide any specific value to the human body until a human based case study gives reason to be optimistic. Cell proliferation was greater than 100% at 0.1-5 and 100-300 μg/ml for Bulbine natalensis and at 0.1μg/ml for Bulbine frutescens. Oddly enough, the rats given the 100 mg dosage showed the opposite behavior. There are very few human studies of the effects of bulbine natalensis, since it is a relatively new health product. Frost tender evergreen perennial, broad sharp pointed fleshy yellow-green leaves. It has long been used in traditional medicines as an aphrodisiac, and is currently being studied with experts looking at its testosterone boosting affects. What’s more, as mentioned above, one study confirmed the safety of it for the same period of a supplement cycle: four weeks. Those rats given 100 mg per kilogram of bodyweight did not see the same results. Bulbine Natalensis is a natural herb that originates from the South and South Eastern parts of Africa. Check out our article on the 7 best natural testosterone boosters. Bulbine Natalensis is an herb known for its aphrodisiac qualities. Yeah I also read, that in rats, to high a dose of Bulbine Natalensis could have the opposite effect. And all of this is achieved at a dose of 50mgs/kg (rat dose), which translates very well to a low human dose, which … It is these plant-based compounds that give Bulbine Natalensis its medicinal properties. ProLensis™ is a well-studied specific extract of bulbine natalensis, with several animal model studies demonstrating the benefit for controlling the hormones testosterone and estrogen – both hormones involved in body augmentation. The prosexual effect of the testosterone booster ProLensis™ (Bulbine natalensis) by John Connor. ), Bulbine Natalensis clocks in at 247% (i.e. At the conclusion of the trial, ProLensis™ was found to be as safe as a maltodextrin placebo. HydroMax or GlycerSize – What Is It & Which Is Better. Since my first post (ver. While this was not the cause of death for the animals, it is of concern because organ shrinkage can lead to organ failure. Sports Nutrition Research is a raw materials provider and supplement formulation team that consults for several dietary supplement manufacturers. In two animal-based studies, Bulbine Natalensis was shown to significantly increase testosterone levels. While it is far more anabolic and androgenic than testosterone, DHT is thought to be one of the primary reasons for male pattern baldness and hair loss. Despite the herb’s documented benefits and uses in traditional medicine, current studies on B. natalensis are scant. Clusters of star-shaped yellow flowers on long thin … It’s easy to see why – the effects of extracts of Bulbine natalensis recorded in animal studies are amazing. In the wellness group, clients regularly devour Bulbine Natalensis with the objective of expanding testosterone and sex drive. Bulbine natalensis is quickly gaining popularity in the sports supplement world. At the conclusion of the trial, ProLensis™ was found to be as safe as a maltodextrin placebo. 730mg for a 200lb person. In one study, 25 mg to 50 mg per kilogram of bodyweight of Bulbine Natalensis was shown to increase testosterone levels as well as serum … Treatment with both leaf gel extracts has previously been demonstrated to increase tensile strength and protein and DNA content in pig dermal wounds. The gel from the leaves of Bulbine natalensis (BN) and Bulbine frutescens (BF) is commonly used as a traditional medicine in South Africa for the treatment of skin wounds and burns. 550mg for a 150lb person. It works more than twice as well as Fadogia, at half the dose. Group A (control) was orally treated with 0.5 mL of disti … Animal studies show that it may increase testosterone, but only at specific doses - too high doses can have a negative impact on long-term health. Rat studies investigating how bulbine natalensis interacts with testosterone note that 50mg/kg (of a 10:1 extraction) appear to be the optimal dosage, and based on Body Surface Area Conversions, this correlates into an estimated human dose of 8mg/kg or:. For more information about ProLensis™ or to order ProLensis™ for your own product line please visit http://www.ProLensis.com or contact info(at)ProLensis(dot)com. Bulbine Natalensis is also known as Ibhucu, Rooiwortel and Ingcelwane. There is evidence from the limited studies undertaken on Bulbine Natalensis to suggest that there is a toxic effect, specifically relating to the liver. Bulbine natalensis is a perennial herb indigenous to South Africa that is currently being marketed as a prosexual product for men. Journal of the International Society of Sports Nutrition (JISSN). Can lead to organ failure compared to baseline, while lowering estrogen by 35 % Research is good. 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